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Marketable securities Schedule of Accrued Expenses Schedule of Accrued Liabilities [Table Text Block] Preferred stock, shares issued Preferred Stock, Shares Issued Operating Lease, Liability Total operating lease liabilities Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total Unrecognized stock-based compensation expense Non-cash lease expense Operating Lease, Right-of-Use Asset, Periodic Reduction Facilities And Other Research And Development Expense Amount of facilities and other research and development expense incurred during the period. Facilities and other research and development Commitments and Contingencies Commitments, contingencies, and other liabilities (see note 7) Weighted Average Number of Shares Outstanding, Diluted Weighted Average Number of Shares Outstanding, Diluted, Total Weighted-average common shares outstanding, diluted (in shares) Lessee, Operating Lease, Term of Contract Lease term Minimum [Member] Minimum Restricted Stock Units And Performance Based Restricted Stock Units [Member] Restricted Stock Units and Performance Based Restricted Stock Units. Unvested RSUs and PRSUs Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Preferred Stock, Shares Outstanding, Ending Balance Preferred Stock, Shares Outstanding, Beginning Balance Accrued Research And Development Costs Current Accrued research and development costs current Research and development costs Fair Value, Recurring [Member] Fair Value, Measurements, Recurring Partnered Programs [Member] Partnered programs. Partnered programs Common stock shares issued Common Stock, Shares, Issued Segment Reporting [Line Items] Income tax provision Income Tax Expense (Benefit) Income Tax Expense (Benefit), Total Counterparty Name [Domain] Related Party Transaction [Line Items] Related-party transactions Restricted Stock Units (RSUs) [Member] RSUs Contract with Customer, Liability Contract with Customer, Liability, Total Deferred revenue, beginning balance Deferred revenue, beginning balance Deferred revenue, ending balance Debt Securities, Available-for-Sale, Amortized Cost Marketable securities, Amortized Cost Marketable securities, Amortized Cost Lessee, Operating Lease, Liability, Undiscounted Excess Amount Less: imputed interest Total other income, net Nonoperating Income (Expense) General and administrative General and Administrative Expense General and Administrative Expense, Total Income Statement [Abstract] Receivables, Net, Current Receivables, Net, Current, Total Accounts receivable Forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Forfeited (in shares) Employee Stock Purchase Plan 2015 [Member] Employee Stock Purchase Plan 2015. 2015 Employee Stock Purchase Plan Contract with Customer, Liability, Increase (Decrease) Amount of increase (decrease) in obligation to transfer good or service to customer for which consideration from customer has been received. or is due. Collaboration revenue recognized Related and Nonrelated Parties [Domain] Net loss per share, basic (in dollars per share) Earnings Per Share, Basic Earnings Per Share, Basic, Total Nancy Vitale Nancy Vitale [Member] Nancy Vitale. Document Period End Date Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Payments to Acquire Property, Plant, and Equipment, Total Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted (in dollars per share) Common Stock, Shares Authorized Common stock shares authorized Statement of Stockholders' Equity [Abstract] Total minimum lease payments Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Lessee Operating Lease Liability To Be Paid AfterYear Four Amount of lessee's undiscounted obligation for lease payment for operating lease due after fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). Thereafter Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Outstanding Total assets Assets Title of 12(b) Security Balance, ending (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Balance, beginning (in shares) Stock Issued During Period, Value, Stock Options Exercised Exercises of stock options Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Summary of Compensation Cost Recognized for All Stock-based Compensation Awards Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Antidilutive Securities, Name [Domain] Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Remainder of 2026 Weighted Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Lessee, Operating Lease, Liability, to be Paid, Year One 2027 Cash and Cash Equivalents [Domain] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term Outstanding Contract with Customer, Asset, after Allowance for Credit Loss, Current Contract with Customer, Asset, after Allowance for Credit Loss, Current, Total Related party collaboration receivable Related party collaboration receivables, beginning balance Related party collaboration receivables, ending balance Nature of Operations [Text Block] Nature of Business Expected Contractual Obligation, Lease Not Yet Commenced Estimated amount of contractual obligation for a lease not yet commenced. Expected contractual obligation for lease not yet commenced Segment Reporting [Table Text Block] Schedule of Reconciliation of Collaboration Revenue and Segment Expenses to Net Loss for Segment Increase (Decrease) in Operating Lease Liability Operating lease liabilities Tau Silencing Gene Therapy Program [Member] Tau silencing gene therapy program. Tau silencing gene therapy program (VY1706) Equity, Attributable to Parent Stockholders' Equity, Beginning Balance Stockholders' Equity, Ending Balance Total stockholders' equity Miscellaneous Other Liabilities Noncurrent Amount of miscellaneous liabilities classified as other, due after one year or the normal operating cycle, if longer. Other non-current liabilities Other Assets, Noncurrent Other non-current assets Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Net loss per share Earnings Per Share [Text Block] Number of Reportable Segments Number of reportable segment Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Schedule of Cash Cash Equivalents and Restricted Cash [Table Text Block] Tabular disclosure of the components of cash, cash equivalents, and restricted cash. Schedule of Reconciliation of Cash, Cash Equivalents, and Restricted Cash Interest Income (Expense), Nonoperating Interest Income (Expense), Nonoperating, Total Interest income Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Marketable securities, Unrealized Gains Neurocrine [Member] Neurocrine. Neurocrine Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Vested (in dollars per share) Proceeds from Stock Options Exercised Proceeds from the exercise of stock options Weighted average incremental borrowing rate Operating Lease Weighted Average Incremental Borrowing Rate Weighted average incremental borrowing rate for operating lease. Statistical Measurement [Axis] Other comprehensive (loss) income: Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract] Area of Real Estate Property Area of additional facility leased Dr Dinah Sah Member Dr Dinah Sah member Dr. Sah Money Market Funds [Member] Money Market Funds Debt Securities, Available-for-Sale, Unrealized Loss Position Debt Securities, Available-for-Sale, Unrealized Loss Position, Total Debt securities, unrealized loss position Entity Interactive Data Current Lessee, Operating Lease, Liability, to be Paid, Year Three 2029 Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Commitments Contingencies and Other Liabilities Common Stock, Value, Issued Common stock, $0.001 par value: 240,000,000 and 120,000,000 shares authorized at June 30, 2026 and December 31, 2025, respectively; 61,273,390 and 59,047,860 shares issued and outstanding at June 30, 2026 and December 31, 2025, respectively US Government Agencies Debt Securities [Member] U.S. Government Agency Securities Total liabilities Liabilities Additions To Contract With Customer Assets Amount of increase to contract with customer assets during the reporting period. Additions Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Schedule of Assets and Liabilities Measured at Fair Value on Recurring Basis Product and Service [Axis] Retained Earnings (Accumulated Deficit) Retained Earnings (Accumulated Deficit), Total Accumulated deficit Fair Value, Inputs, Level 3 [Member] Significant Unobservable Inputs (Level 3) Loss on disposal of fixed assets Gain (Loss) on Disposition of Property Plant Equipment Gain (Loss) on Disposition of Property Plant Equipment, Total Cash and cash equivalents, Fair Value Cash and Cash Equivalents, Fair Value Disclosure Accounts payable Increase (Decrease) in Accounts Payable Increase (Decrease) in Accounts Payable, Total Operating Expenses Total operating expenses Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Vesting period Stock Issued During Period, Shares, New Issues Issuance of common stock from at-the-market sales agreement, net of issuance costs (in shares) Restricted Cash Restricted Cash, Total Restricted cash included in deposits and other non-current assets Money Market Funds and Marketable Securities Amortized Cost Basis Represents the value of money market funds and marketable securities on amortized cost basis. Total cash equivalents and marketable securities Share Based Compensation Arrangement By Share Based Payment Award Maximum Shares Authorized Excluding Shares Reserved Under Previous Plan Share based compensation arrangement by share based payment award maximum shares authorized excluding shares reserved under previous plan. Maximum shares authorized excluding shares reserved under previous plan Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price Cancelled or forfeited (in dollars per share) Related Party Transactions [Abstract] Related-Party Transactions Long-Lived Asset, Class [Axis] Fair Value Hierarchy and NAV [Axis] Assets, Fair Value Disclosure [Abstract] Assets, Fair Value Disclosure Debt Securities, Available-for-Sale Debt Securities, Available-for-Sale, Total Marketable securities, Fair Value Operating lease liabilities Operating Lease, Liability, Current Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Balance, beginning (in dollars per share) Balance, ending (in dollars per share) Internal Research And Development Expense Internal research and development Amount of internal research and development expense incurred during the period. Investments, Fair Value Disclosure [Abstract] Fair Value Total liabilities and stockholders' equity Liabilities and Equity Share Based Compensation Arrangement By Share Based Payment Award Authorized Shares Reserved Under Previous Plan Share based compensation arrangement by share based payment award authorized shares reserved under previous plan. Shares reserved under previous plan Lessee, Operating Lease, Liability, to be Paid, Year Two 2028 Research and Development Expense Research and Development Expense, Total Research and development Significant Agreements [Abstract] Significant agreements. Lessee, Lease, Description [Table] Document Fiscal Period Focus Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Net decrease in cash, cash equivalents, and restricted cash Entity Current Reporting Status Use of Estimates, Policy [Policy Text Block] Use of Estimates Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Fair Value, Inputs, Level 1 [Member] Quoted Prices in Active Markets for Identical Assets (Level 1) Accounts payable Accounts Payable, Current Accounts Payable, Current, Total Schedule of outstanding potentially dilutive securities that have been excluded in the calculation of diluted net loss per share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Financial Instrument [Axis] Debt securities, contractual maturity period Debt Securities Contractual Maturity Period Contractual maturity period of a marketable debt security. Total cash equivalents and marketable securities Assets, Fair Value Disclosure Other non-current assets Increase (Decrease) in Other Noncurrent Assets Document Transition Report Non-profit organization agreement NonProfitAgreement [Member] NonProfitAgreement [Member]. Commitments and Contingencies Disclosure [Abstract] Commitments, Contingencies, and Other Liabilities Current liabilities: Liabilities, Current [Abstract] Share-Based Payment Arrangement [Abstract] Common Stock [Member] Common Stock Money Market Funds and Marketable Securities Fair Value Represents the fair value of money market funds and marketable securities. Total money market funds and marketable securities Statistical Measurement [Domain] Marketable Securities Marketable Securities, Total Marketable securities Nonoperating Income (Expense) [Abstract] Other income, net: Equity, Attributable to Parent [Abstract] Stockholders' equity: Weighted Average Number of Shares Outstanding, Basic Weighted Average Number of Shares Outstanding, Basic, Total Weighted-average common shares outstanding, basic (in shares) Assets [Abstract] Lease expense Operating Lease, Expense Entity Central Index Key Antidilutive Securities [Axis] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Exercisable Current Fiscal Year End Date Increase (Decrease) in Accrued Liabilities Increase (Decrease) in Accrued Liabilities, Total Accrued expenses Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Document Quarterly Report Cash and Cash Equivalents [Axis] Fair Value, Inputs, Level 2 [Member] Significant Other Observable Inputs (Level 2) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Outstanding (in dollars per share) Outstanding (in dollars per share) Cash and Cash Equivalent [Table] Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Entity Incorporation, State or Country Code Earnings Per Share, Diluted Earnings Per Share, Diluted, Total Net loss per share, diluted (in dollars per share) Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Net loss Net loss Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture, Total Issuance of common stock under ESPP Preferred stock, $0.001 par value: 5,000,000 shares authorized at June 30, 2026 and December 31, 2025; no shares issued and outstanding at June 30, 2026 and December 31, 2025 Preferred Stock, Value, Outstanding Commitments and Contingencies Disclosure [Text Block] Commitments, Contingencies, and Other Liabilities Long-Lived Asset, Class [Domain] Cash, Cash Equivalents, and Short-Term Investments Cash, Cash Equivalents, and Short-Term Investments, Total Cash, cash equivalents, and marketable securities Lease Obligation Lease Disclosure [Text Block] The entire disclosure of information about leases. Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Total other comprehensive (loss) income Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss Measurement Frequency [Domain] Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block] Schedule of Related Party Collaboration Receivable and Deferred Revenue Equity Components [Axis] Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Cash flow from investing activities Collaborative Arrangement Disclosure [Text Block] Significant Agreements Statement of Cash Flows [Abstract] Fair Value Hierarchy and NAV [Domain] Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Cash and Cash Equivalents Disclosure [Text Block] Cash Equivalents and Available-for-Sale Marketable Securities Unrealized Losses, Less than 12 months - Marketable securities Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Fair Value Disclosures [Text Block] Fair Value Measurements Preferred stock, authorized Preferred Stock, Shares Authorized Cash and Cash Equivalents [Line Items] Cash Equivalents and Available-for-Sale Marketable Securities [Line Items] Other Research and Development Programs And Platforms [Member] Other research and development programs and platforms. Other programs and platforms OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Unrealized gain (loss) on available-for-sale securities, net of tax Net unrealized (loss) gain on available-for-sale securities Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Antidilutive securities Counterparty Name [Axis] Number of Operating Segments AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Loss Performance Based Restricted Stock Units [Member] Performance based restricted stock units. PRSUs Accrued expenses Accrued Liabilities, Current Total Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Outstanding, beginning balance (in shares) Outstanding, ending balance (in shares) Total Revenue Recognized from Both the Beginning Balance and Current Period Increase in Contract Liability Amount of revenue recognized that was previously included in balance of obligation to transfer good or service to customer for which consideration from customer has been received or is due, and from current period increase in contract liability. Deductions Vesting of Restricted Common Stock in Shares Represents the number of vested restricted common stock. Vesting of restricted stock units (in shares) Document Type Operating Lease, Lease Income [Table Text Block] Summary of Operating Sublease Income Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Cash flow from operating activities Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration] Liabilities and Equity [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Total Cancelled or forfeited (in shares) Lessee, Lease, Description [Line Items] Outstanding stock options Operating Income (Loss) Operating loss Non Profit Organization Milestone Payment Liability Non Profit Organization Milestone Payment Liability. Milestone payment liability Segment Reporting [Table] Entity File Number Employee Stock Incentive Plan 2025 [Member] Employee Stock Incentive Plan 2025. 2025 Stock Incentive Plan Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Summary of Future Minimum Lease Payments Due Under Operating Leases Location, Statement of Income, Balance [Axis] Retained Earnings [Member] Accumulated Deficit Entity Registrant Name Accounting Policies [Abstract] Summary of significant accounting policies and basis of presentation Depreciation Depreciation, Total Depreciation Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net loss Entity Address, Address Line One Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Accrued Expenses Neurocrine Collaboration Agreement 2019 and 2023 [Member] Neurocrine collaboration Aareement 2019 and 2023 2019 and 2023 Neurocrine Collaboration Agreement Exercises of stock options (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Exercised (in shares) Exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Assets, Current Total current assets Fair Value, Recurring and Nonrecurring [Table] Segments [Axis] Related Party Transactions Disclosure [Text Block] Related-Party Transactions Entity Small Business Forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Significant Accounting Policies [Text Block] Summary of significant accounting policies and basis of presentation Employee-related Liabilities, Current Employee-related Liabilities, Current, Total Employee compensation costs Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share Non Profit Organization Research And Development Maximum Funding Capacity Non Profit Organization Research and Development Maximum Funding Capacity. Maximum funding Earnings Per Share [Abstract] Net loss per share Net loss per share Share-Based Payment Arrangement, Option, Activity [Table Text Block] Summary of Stock Option Activity Lessee, Operating Lease, Liability, to be Paid, Year Four 2030 2023 Neurocrine Collaborative Agreement and 2019 Neurocrine Collaborative Agreement [Member] 2023 neurocrine collaborative agreement and 2019 neurocrine collaborative agreement. 2023 Neurocrine Collaboration Agreement and 2019 Neurocrine Collaboration Agreement Plan Name [Axis] Loss Contingency Accrual Loss Contingency Accrual, Ending Balance Loss Contingency Accrual, Beginning Balance Contingency reserves for litigation liabilities Product and Service [Domain] Measurement Frequency [Axis] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Cash flow from financing activities Accrued Liabilities, Current [Abstract] Accrued Expenses Marketable Securities, Noncurrent Marketable securities, non-current Entity Tax Identification Number Equity Component [Domain] Stock Purchase Plan Payroll Percent Deduction Stock purchase plan payroll percent deduction. Percentage of payroll deduction Entity Address, City or Town Increase (Decrease) in Contract with Customer, Liability Deferred revenue Stock Issued During Period, Value, New Issues Issuance of common stock from at-the-market sales agreement, net of issuance costs Restricted Cash, Noncurrent Restricted cash Segments [Domain] Entity Common Stock, Shares Outstanding Marketable Securities [Table Text Block] Schedule of Cash Equivalents and Available-for-Sale Marketable Securities Commercial Paper Commercial Paper [Member] Segment Reporting, Expense Information Used by CODM, Description Antidilutive Security, Excluded EPS Calculation [Table] Contract with Customer, Liability, Current Deferred revenue Purchases of marketable securities Payments to Acquire Marketable Securities Statement [Table] Share-Based Payment Arrangement, Expense Stock-based compensation Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Loss before income taxes Entity Shell Company Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash provided by investing activities Single Reportable Segment [Member] Single reportable segment. Single reportable segment Statement [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Vested Vested (in shares) Maximum [Member] Maximum Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised Proceeds from the purchase of common stock under ESPP Anti-tau antibody program (VY7523) Anti Tau Antibody Program [Member] Anti tau antibody program. Principles of Consolidation Consolidation, Policy [Policy Text Block] APIC, Share-Based Payment Arrangement, Option, Increase for Cost Recognition Stock-based compensation expense Eligible Period To Purchase Shares Eligible period to purchase shares. Period to purchase shares Granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Assets, Current [Abstract] Current assets: Accrued Professional Fees, Current Professional services Leases [Abstract] Document Fiscal Year Focus Amortization of premiums and discounts on marketable securities Accretion (Amortization) of Discounts and Premiums, Investments Common Stock, Shares, Outstanding Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Common stock share outstanding Collaborative Arrangement and Arrangement Other than Collaborative [Table] Financial Instruments [Domain] Related Party [Member] Related Party Operating lease liabilities, net of current portion Operating Lease, Liability, Noncurrent SOD1 silencing gene therapy program Sod1 Silencing Gene Therapy Program [Member] Sod1 silencing gene therapy program. 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Unrealized Gains and Losses Debt Securities, Available-for-Sale [Abstract] Amortized Cost Corporate Bond Securities [Member] Corporate Bonds City Area Code Nature of business Organization, Consolidation and Presentation of Financial Statements [Abstract] Proceeds from Issuance of Common Stock Proceeds from the issuance of common stock from at-the-market sales agreement, net of issuance costs Number of marketable securities Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Operating Expenses [Abstract] Operating expenses: FA Program and Discovery Program Three [Member] FA program and discovery program three. FA Program and Discovery Program 3 External Research And Development Expense Amount of external research and development expense incurred during the period. External research and development Common Stock, Par or Stated Value Per Share Common stock, par value (in dollars per share) Remaining Contractual Life [Abstract] Remaining contractual life. Remaining Contractual Life Cash and Cash Equivalents [Abstract] Cash Equivalents and Available-for-Sale Marketable Securities Facility 75 Hayden Avenue [Member] Represents the lease at 75 Hayden Avenue. Lexington Facility Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term Exercisable Total current liabilities Liabilities, Current Segment Information Segment Reporting [Text Block] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative Trading Symbol Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Granted (in shares) Entity Emerging Growth Company Additional Paid-in Capital [Member] Additional Paid-In Capital Shares Issued, Shares, Share-Based Payment Arrangement, after Forfeiture Shares Issued, Shares, Share-Based Payment Arrangement, after Forfeiture, Total Issuance of common stock under ESPP (in shares) Plan Name [Domain] US Treasury Securities [Member] U.S. Treasury Notes Cover [Abstract] Operating Lease, Weighted Average Remaining Lease Term Weighted average remaining lease term Non Profit Organization Research And Development Multiple Non Profit Organization Research and Development Multiple. Funding multiple Nonvested Restricted Stock Shares Activity [Table Text Block] Summary of Status and Changes in Unvested Restricted Stock and Performance-based Restricted Stock Units Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated other comprehensive (loss) income Share-Based Payment Arrangement, Noncash Expense Share-Based Payment Arrangement, Noncash Expense, Total Stock-based compensation expense Additional Paid in Capital Additional Paid in Capital, Total Additional paid-in capital Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Fair Value Disclosures [Abstract] Cash and Cash Equivalent Cash and Cash Equivalent, Total Cash and cash equivalents Deductions To Contract With Customer Assets Amount of decrease to contract with customer assets during the reporting period. Deductions Aggregate Intrinsic Value [Abstract] Aggregate intrinsic value. Aggregate Intrinsic Value Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Payables and Accruals [Abstract] Entity Filer Category Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description Increase Decrease in Collaboration Receivables Increase decrease in collaboration receivables Related party collaboration receivable Marketable securities Marketable Securities, Current Accounts receivable Increase (Decrease) in Accounts Receivable Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization, Total Property and equipment, net Revenue from Contract with Customer, Excluding Assessed Tax Collaboration revenue Shares, Outstanding Shares, Outstanding, Ending Balance Shares, Outstanding, Beginning Balance Segment Reporting [Abstract] Entity Address, Postal Zip Code Statement of Financial Position [Abstract] Condensed Consolidated Balance Sheets Local Phone Number